ICCS Scientific Advisory Committee

Dr. Katie Paul Friedman leads numerous initiatives advancing the application of informatics, bioinformatics, and new approach methodologies (NAMs) to chemical safety science. Her work focuses on harnessing computational and experimental tools to accelerate understanding of chemical exposures, biological activity, and potential health outcomes.

Dr. Paul Friedman previously served as a Supervisory Computational Toxicologist at the U.S. Environmental Protection Agency’s Center for Computational Toxicology and Exposure. There, she oversaw the ToxCast program and led research applying NAMs to chemical safety assessment, with emphasis on endocrine bioactivity, developmental neurotoxicity prediction, in vitro kinetics, and the evaluation of variability across alternative and traditional toxicity data. She also worked as a regulatory toxicologist at Bayer CropScience, contributing expertise in regulatory science and risk assessment.

Dr. Paul Friedman has been deeply engaged in multi-stakeholder collaborations to develop adverse outcome pathways, establish alternative testing strategies, and advance regulatory acceptance of NAMs. She has provided technical leadership to Federal Advisory Committee reviews and global consortia such as the Accelerating the Pace of Chemical Risk Assessment. Her laboratory background includes development of high-throughput screening assays and application of in vitro and in vivo systems to investigate thyroid and metabolic adverse outcome pathways relevant to human health.

She earned her Ph.D. in Toxicology from the University of North Carolina at Chapel Hill and has authored more than 75 peer-reviewed publications.