ICCS Educational Resources and Training
INTERNATIONAL COLLABORATION ON COSMETICS SAFETY
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ICCS TRAINING
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NAMs 101
Designed for an audience new to NAMs and NGRA frameworks, this tool will be available soon.
NAMs 101
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NGRA Case Studies: Benzophenone-4
Benzophenone-4 case study given by Matthew Dent of Unilever. Japanese captions are available through closed captioning.
NGRA Case Studies: Benzophenone-4
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Skin Sensitization Assessment Using New Approach Methods for Substances in Cosmetics and Personal Care Products
This initial BPG outlines a structured workflow to support safety assessors in applying NAMs for skin sensitization without relying on new animal tests.
Skin Sensitization Assessment Using New Approach Methods for Substances in Cosmetics and Personal Care Products
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Updates on New Approach Methodologies (NAMs) Applied to Human and Environmental Safety Webinar Serie (Portuguese / Spanish)
Updates on New Approach Methodologies (NAMs) Applied to Human and Environmental Safety Webinar Serie (Portuguese / Spanish)
EXTERNAL TRAINING
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AFSA Master Class in Animal-Free Safety Assessment Collaboration
The course covers the entire risk assessment process in 10 modules (8 are currently available). The course is freely available online and can be taken at your own pace.
AFSA Master Class in Animal-Free Safety Assessment Collaboration
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ASCCT Webinars
The American Society for Cellular and Computational Toxicology (ASCCT) is a scientific society dedicated to the promotion of toxicology testing and research that reduces and replaces the use of animals. This webpage compiles upcoming webinars from ASCCT and its partners.
ASCCT Webinars
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CTPA Online Learning Platform
CTPA has created this e-learning course on 'Safety Assessment for Cosmetic Products'. The course consists of the following seven modules, each delivered by industry experts.
CTPA Online Learning Platform
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IIVS Training
The Practical Methods training program provides a variety of education and training opportunities, from in-person intensive hands-on courses to lectures, panel discussions, webinars, and consultations that are relevant across all sectors and can include a range of non-animal methods.
IIVS Training
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NURA Training
NURA (NAM Use for Regulatory Application) is a free training resource aimed at expanding the use of non-animal methods in regulatory toxicology.
NURA Training
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Persistence Assessment Tool (PAT) Training Session
This training session provides an in-depth look at the use of the tool, including the background and purpose, an overview of features and workflow, and a walkthrough of an example assessment.
Persistence Assessment Tool (PAT) Training Session
Additional Resources
Journals
- Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients
- Next generation risk assessment: an ab initio case study to assess the systemic safety of the cosmetic ingredient, benzyl salicylate, after dermal exposure
- Next-generation risk assessment read-across case study: application of a 10-step framework to derive a safe concentration of daidzein in a body lotion
- Next generation risk assessment for occupational chemical safety – A real world example with sodium-2-hydroxyethane sulfonate
- Development of a next generation risk assessment framework for the evaluation of skin sensitisation of cosmetic ingredients
- A Next-Generation Risk Assessment Case Study for Coumarin in Cosmetic Products
- Applying a next generation risk assessment framework for skin sensitisation to inconsistent new approach methodology information
- Case Study on the Use of Integrated Approaches for Testing and Assessment for skin sensitisation: Demonstrating the Next Generation Risk Assessment Framework using Geraniol
- Next generation risk assessment for skin sensitisation: A case study with propyl paraben
- Read-across can increase confidence in the Next Generation Risk Assessment for skin sensitisation: A case study with resorcinol
- Skin sensitisation prediction using read-across, an illustrative next generation risk assessment (NGRA) case study for vanillin
- A hypothetical skin sensitisation next generation risk assessment for coumarin in cosmetic products
- Incorporating integrated testing strategy (ITSv1) defined approach into read-across (RAx) in predicting skin sensitization potency: ITSv1-based RAx
- Use of in vitro ADME methods to identify suitable analogs of homosalate and octisalate for use in a read-across safety assessment
- ADME characterization and PBK model development of 3 highly protein-bound UV filters through topical application
Conference Presentations
- Models Evaluating the direct-Release of Cosmetic Ingredients (MERCI) - presented SETAC Europe 34th Annual Meeting 2024
- Next Generation Risk Assessment for Occupational Chemical Safety – a Real World Example with Sodium-2-hydroxyethane sulfonate - presented at BTS Annual Congress 2024
- Towards NGRA Skin Sensitisation – Case study on diethanolamine (DEA) - presented at the IDEA workshop on New Approach Methodologies (NAMs) – Application of the Reference Chemical Potency List (RCPL)
- Decision making in Next Generation Risk Assessment (NGRA) for Skin Sensitisation: How useful Read-Across Analogue Data can be - presented at SOT 63rd Annual Meeting and ToxExpo 2024