Inolex and U.K.'s Cosmetic, Toiletry & Perfumery Association Join ICCS

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September 14, 2023

NEW YORK and PHILADELPHIA and LONDON – Inolex, a sustainable ingredient designer for health, beauty, and wellness, and the Cosmetic, Toiletry and Perfumery Association (CTPA), the UK trade association representing companies involved in making, supplying, and selling cosmetics and personal care products have become members of the International Collaboration on Cosmetics Safety (ICCS). This marks a significant stride for both organizations in their dedication to promoting the use of animal-free testing methods for evaluating the safety of cosmetics and their components, both in terms of human health and environmental impact.

ICCS is a global initiative focused on the adoption of animal-free assessments of cosmetics, and their ingredients for human health and environmental safety. Headquartered in New York, the ICCS brings together scientists and industry experts to drive greater global awareness and confidence in animal-free science assessments. ICCS membership encompasses a diverse range of stakeholders, including cosmetic and chemical trade and research associations, non-governmental organizations, and cosmetic product and ingredient manufacturers.

Erin Hill, ICCS President and CEO, expressed the significance of this development, "The inclusion of Inolex and CTPA as members is another important step towards driving greater global awareness in animal-free science. With these two notable organizations we will continue to build on our progress for the accelerated uptake of non-animal methodologies."

Inolex and CTPA are among an array of renowned international corporations and organizations including global beauty companies and animal protection groups that stand with the ICCS mission of applying animal-free test methods to ensure cosmetic safety.

"We are pleased to partner with ICCS on their mission and science-backed approach to eliminate animal testing in beauty and personal care. Together with like-minded organizations, we can move the industry in a forward direction to make responsible alternatives for assessing ingredient and consumer product safety the norm," said Katie Sminkey, Product Stewardship Manager at Inolex.

Inolex is a global company that designs ingredients for the personal care and cosmetics industries. With sustainability central to all it does, Inolex is shaping the beauty and personal care industry with technology rooted in green chemistry. Inolex is committed to animal welfare and does not sell animal-products or animal byproduct-derived products. Inolex also does not test their products on animals. Since 2018, the Inolex portfolio is 100% vegan-friendly and cruelty-free.

"I am delighted that CTPA has become a member of ICCS. CTPA is proud to champion the use of non-animal test methods to ensure chemical safety. Being able to do this at a global level in partnership with the key stakeholders at ICCS is so important and exciting," said Dr. Emma Meredith, Director-General of CTPA.

CTPA is the UK association representing all types of companies involved in making, supplying, and selling cosmetics and personal care products and suppliers to the industry. CTPA is the voice of the UK cosmetics industry and its essential contribution to health, hygiene, and wellbeing. CTPA has proven its commitment to advancing animal-free safety assessments by teaming with experts to increase education and awareness of New Approach Methodologies (NAMs) and Next Generation Risk Assessment (NGRA).

ICCS continues to work with all stakeholders across the world to accelerate the transition to global use and acceptance of animal-free science for human safety and environmental assessment.

About ICCS
The International Collaboration on Cosmetics Safety (ICCS) is a global initiative focused on advancing the adoption of animal-free safety assessment approaches for cosmetics, personal care products and their ingredients. ICCS brings together scientists and experts from cosmetics manufacturers and suppliers, industry associations, and animal protection organizations to drive greater global awareness to accelerate widespread use of animal-free science through research, education, and regulatory engagement. www.iccs-cosmetics.org

About Inolex
Inolex is a fiercely independent company that designs sustainable ingredients for health, beauty, and wellness. We don't swim with the current; we create it. We envision and realize solutions to advance the needs of our customers. We challenge ourselves and the industry to think differently. Honoring nature, we design emerging technologies that ensure the safe and optimum performance of leading brands in more than 85 countries. Our designers are guided by the Principles of Green Chemistry, to invent the future of sustainable ingredient platforms. By balancing conscious science with nature and artistry, our imaginative approaches become the building blocks for exceptional products that care for people and our planet. We are Inolex. Thinkers, Designers, Creators, and Rebels. www.inolex.com

About CTPA
CTPA's membership, from multi-nationals to SMEs, represents over 85% of the UK market by retail sales value. We promote best practice and advise companies about the strict legal framework for cosmetics. The Association represents industry views to the UK Government and external stakeholders and also provides information to the media on issues relating to the safety of cosmetic products. When the UK left the European Union, CTPA engaged immediately with the UK Government to ensure the rigorous bans on the testing of cosmetic products and their ingredients on animals remained under the new UK regulatory framework for cosmetics and CTPA continues to promote regulatory acceptance of animal-free test methods for any chemicals that could be used in cosmetics. www.ctpa.org.uk

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Consumer Healthcare Products Association Joins the International Collaboration on Cosmetics Safety

October 16, 2025

The International Collaboration on Cosmetics Safety (ICCS) today announced that the Consumer Healthcare Products Association (CHPA) has joined its global network of non-governmental, trade/research organizations, and industry partners dedicated to advancing animal-free safety assessments for cosmetics and personal care products. “We are thrilled to welcome CHPA to ICCS,” said Erin Hill, President and CEO of ICCS. “Their leadership in consumer health and dedication to regulatory science will further strengthen our collective mission to promote innovative, human- and environmentally relevant safety assessment strategies. Especially at a time in the U.S., when the Food and Drug Administration is emphasizing reliable alternatives to animal testing, ICCS and its members are united in driving collaborative, science-led approaches that advance public health protection.” Jay Sirois, PhD, Vice President of Scientific and Regulatory Affairs at CHPA, said: “Joining ICCS reflects our shared commitment to modernizing safety evaluation across product categories. This collaboration will help ensure that scientific innovation and regulatory progress move hand in hand, supporting the ongoing development of safe, effective, and trusted self-care products.” The ICCS–CHPA collaboration comes at a pivotal moment following the FDA’s September 30, 2025, communication in which the Agency explicitly encouraged the development of new, reliable alternatives to animal testing for sunscreens. In response, ICCS is offering its support to help the FDA realize its plans for implementing New Approach Methodologies (NAMs) in sunscreen safety assessments. ICCS aims to help ensure that the FDA’s commitment to modern, animal-free science, already demonstrated in other regulatory areas, is fully realized in the sunscreen space. ICCS’ aligned efforts focus on advancing modern, science-based approaches to safety assessment that incorporate new technologies and internationally recognized best practices. The organization also supports a consistent and transparent regulatory framework that enables the broader application of NAMs across product categories. Through continued collaboration and knowledge sharing among regulators, industry, and NGOs, ICCS works to strengthen public health protection while fostering scientific innovation and regulatory modernization. By strengthening partnerships and advancing modern scientific tools, ICCS and its members are setting the stage for lasting progress in regulatory science and public health protection. About ICCS The International Collaboration on Cosmetics Safety is a global initiative headquartered in New York. It brings together scientists from industry, academia, and non-governmental organizations to promote the adoption and regulatory acceptance of animal-free safety science through education, research, and collaboration. Visit www.iccs-cosmetics.org About CHPA The Consumer Healthcare Products Association (CHPA), founded in 1881, is the national trade association representing the leading manufacturers and marketers of consumer healthcare products, including over-the-counter (OTC) medicines, dietary supplements, and OTC medical devices. CHPA is committed to empowering self-care by ensuring that Americans have access to products they can count on to be reliable, affordable, and convenient, while also delivering new and better ways to get and stay healthy. Visit www.chpa.org

ICCS Debuts Best Practice Guidance Series Focus on Skin Sensitization Without Animal Testing

July 21, 2025

The International Collaboration on Cosmetics Safety (ICCS) announces its first-ever Best Practice Guidance (BPG): “Skin Sensitization Assessment: Using New Approach Methods for Substances in Cosmetics and Personal Care Products.” This document marks the inaugural publication in a new series of ICCS Best Practice Guidance documents, developed to support the global transition to animal-free safety science. ICCS was invited to present the BPG at the Integrated Strategies for Safety Assessment of Cosmetics Joint Regulators-Industry Workshop hosted by the International Cooperation on Cosmetics Regulation (ICCR) on July 11, where regulators from more than 12 countries convened to advance non-animal methodologies. “This guidance reflects the collective expertise of ICCS members who came together to align on the development of this unique guidance,” said Erin Hill, President & CEO of ICCS. “It’s a key example of our mission to build global capacity and accelerate the uptake of animal-free safety assessments. We greatly appreciate the opportunity to collaborate with the ICCR to hear their input on the workflow in the document.” Grounded in Next Generation Risk Assessment (NGRA) principles, the BPG offers a structured, science-based workflow that includes practical steps from problem formulation, exposure assessment, data evaluation, to transparent decision-making. It is especially suited for safety assessors experienced in traditional methods but new to using NAMs. What Makes the ICCS BPG Unique This BPG builds on existing international frameworks—such as OECD test guidelines and ICCR principles—by integrating them into a cohesive, assessor-friendly workflow. It emphasizes practical use and real-world safety scenarios and is specifically designed for regulatory safety assessments of cosmetics and personal care products. Notably, the guidance provides tools for transparent decision-making, uncertainty characterization, and exposure-based waiving, offering assessors clear and pragmatic support for transitioning to animal-free science. Key Highlights of the BPG: Step-by-step workflow to guide assessors through skin sensitization hazard and safety assessments without new animal tests. Integration of in silico, in chemico, and in vitro methods, including those aligned with OECD Test Guidelines. Designed for regulatory use, especially for assessors transitioning from animal to non-animal approaches. The full guidance is now freely available for download on the ICCS Website . Looking Ahead The Skin Sensitization BPG is the first in a planned suite of ICCS Best Practice Guidance documents. Forthcoming documents planned are: eye and skin irritation, read-across, thresholds of toxicological concern (TTC), physiologically based kinetic (PBK) modeling, exposure-based waiving, and environmental safety endpoints. These guidance documents will continue to support ICCS’ goal of equipping the international community with practical tools for modern, human-relevant, and animal-free safety assessments.

ICCS 2024 Annual Report

June 26, 2025

Explore the ICCS 2024 Annual Report! Dive into a year of progress in fostering regulatory collaboration, promoting harmonization, and strengthening global capacity. See how ICCS and its members contributed to advancing NAMs and NGRA—and helped shape a more modern, animal-free future.