AquaTox:  Chronic Fish Toxicity Case Studies Toward a Best Practice Guidance Document

The project is driven by a tiered approach, starting to identify data gaps and developing solutions to support regulatory registration dossiers, but ultimately, aiming towards applying environmental NGRA:

1. Evaluate applicability of New Approach Methodologies (NAMs) for chronic fish toxicity through multiple cosmetic ingredient case studies.
2. Identify data gaps and develop solutions to support regulatory dossiers and reduce reliance on vertebrate testing.
3. Produce an ICCS best practice guidance document including flow charts and case studies to promote regulatory acceptance of NAMs.