Skin Sensitization:  Uncertainty Assessment in the Skin Sensitization NGRA

Project Details

Skin Sensitization Working Group

Project Leads:

  • Petra Kern, P&G


Objectives

The project’s aim is to further build user and stakeholder confidence in the NGRA by developing a plausible, realistic and transparent approach to evaluate NAM-based NGRA uncertainties that informs the appropriateness of the MoE. The objectives are to:

  1. Develop a (semi-)quantitative uncertainty assessment approach to derive a MoE by mapping all potential sources of uncertainty within the NAM-based skin sensitization NGRA
  2. Assess the usefulness of the approach via case studies
  3. Inform and engage the scientific community and stakeholders via dissemination activities