ICCS Environmental Health

Review of available standard and novel experimental methods, addressing their applicability to assessment of water-soluble and water-dispersible polymer biodegradation; identify gaps and opportunities for research to improve available experimental methods and approaches​.

Review of In Silico methods with focus on their applicability to predict degradation of polymers, considering possible breakdown processes and degradation products; identify gaps and opportunities for research to improve In Silico methods for polymer degradation predictions.

Mapping of new environmental NAMs from literature for future regulatory acceptance with machine learning tools: Collection and categorization of literature​, method evaluation and database construction​, recommendations for regulatory acceptance​.

Review of existing regulations and approaches, criteria, and standards for assessing the biodegradability of cosmetic, personal care and homecare products​.

Review available test methods related to acute and chronic coral toxicity for different life stages (e.g., larvae, juvenile, adults)​.

Workshop to develop a roadmap to advance (bio)degradation assessments of water soluble and dispersible polymers.

Create an environmental next-generation risk assessment framework with case-studies to “stress-test” selected scientific approaches towards reaching a safety decision​.

Create a formatted database for future in silico tool developments, capturing the scientific literature on water soluble and dispersible biodegradation, including references to abiotic end enzymatic transformation pathways.

Generate case studies applying NAMs for chronic fish toxicity to cosmetic ingredients, identify critical gaps, and consolidate insights into an ICCS best practice guidance document supporting regulatory acceptance and future IATA development with other partners.